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Overview: Simian Immunodeficiency Virus (SIV) is thought to be a precursor to HIV. This multi-part case study explores changes in SIV in different chimpanzee populations and how researchers use this information to test hypotheses about the origins of HIV. Author/Source: Kosal, Erica F. Grade level: 13-16 Time: 1.5 to 2 hrs. Concepts: Present-day species evolved from earlier species; the relatedness of organisms is the result of common ancestry. Similarities among existing organisms (including morphological, developmental, and molecular similarities) reflect common ancestry and provide evidence for evolution. Speciation is the splitting of one ancestral lineage into two or more descendent lineages. A hallmark of science is exposing ideas to testing. Classification is based on evolutionary relationships. Teacher background: Speciation Nature of Science

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