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Overview: In October 2011, the World Health Organization announced that tuberculosis cases are on the decline for the first time in at least 20 years. Our battle against this ancient disease has been fought, in part, through the use of antibiotics like streptomycin. This news brief describes the 1.8 billion year evolutionary history behind these drugs. Author/Source: UC Museum of Paleontology Grade level: 13-16 Time: 15 minutes Teaching tips: Use this resource to relate evolutionary concepts to the topics of cellular organelles (specifically, ribosomes) and DNA translation (or get more suggestions for incorporating evolution throughout your biology syllabus). This article includes a set of discussion and extension questions for use in class, including advanced items for undergraduates. It also includes hints about related lessons that might be used in conjunction with this one. Get more tips for using Evo in the News articles in your classroom. Concepts: Present-day species evolved from earlier species; the relatedness of organisms is the result of common ancestry. The early evolutionary process of eukaryotes included the merging of prokaryote cells. As with other scientific disciplines, evolutionary biology has applications that factor into everyday life, for example in agriculture, biodiversity and conservation biology, and medicine and health. Teacher background: Relevance

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